Livercancer or Hepatocellular carcinoma (HCC) is one of the commonest cancers in the
world which have a high incidence of Hepatitis B infection. Apart from
Hepatitis B, it may be caused by other diseases that lead to cirrhosis of the
liver such as Hepatitis C infection, and alcohol abuse.
Unfortunately, like many other
cancers, liver cancer may go undetected until a late stage. It is often brought
to attention by an ultrasound or CT scan done for pain in the upper abdomen or
another unrelated symptom. Liver cancers are malignant tumors that grow on the
surface or inside the liver. Typers of liver cancer areHepatocellular Carcinoma
, Cholangiocarcinoma , Hepatoblastoma and Angiosarcoma or Hemangiosarcoma
Each person is unique, each
cancer is unique
No
treatment or treatment plan is right for every person or every cancer. Only by
working closely with their doctor can patients decide what treatment or
combination of treatments may best fit their unique situation.
Factors in treating liver cancer
Recommended
treatments for liver cancer can depend on:
·
a patient’s age, overall health, physiology and
pre-existing conditions
·
the number of tumors and degree of invasion of other
tissues (stage)
·
the degree of liver damage or dysfunction
·
the tumor location(s) and proximity to major blood
vessels, bile ducts or other organs
·
the type of cancer, including whether it is primary or
secondary
·
the degree of cancer cell resemblance to surrounding
tissue (grade)
·
a patient’s individual preferences
Treatments
for cancer may involve:
·
surgical removal of cancerous tissue
·
destroying cancerous tissue with drugs or other chemicals
·
using hot or cold energy, such as from microwaves,
ultrasound, radiofrequency or super-cooled high pressure gases
·
radiation
Many
treatment plans attack cancer by using multiple therapies, enabling
customization to the unique physiologies, conditions and preferences of
patients.
Resection methods
Surgeons often use two methods to perform a
surgical liver resection: laparoscopic surgery or open surgery. A laparoscopic
surgery is a minimally invasive procedure that allows the surgeon to access the
liver through a few small "porthole" incisions. The surgeon performs
the procedure using a laparoscope, a device that provides a camera view of the
liver. The surgeon will also access the organ through ports for the surgical
instruments. During open surgery, the surgeon makes a larger incision in the
abdomen to access the liver directly.
Chemotherapy is a treatment that uses drugs to destroy
cancerous tissue in the body. Normal cells typically grow and die in a
controlled cycle; cancerous cells keep dividing, uncontrollably forming more
cells. Chemotherapy drugs destroy cancer cells by stopping them from growing or
multiplying. These drugs can also be harmful to healthy cells, especially those
that divide quickly. This may cause side effects such as hair loss. Healthy
cells usually can repair themselves after chemotherapy.
Some types of cancer respond better than
others to chemotherapy. The chemotherapy drug(s) selected depend on the type of
cancer and other factors.
Because some drugs work better in combination
with others than alone, two or more drugs are often given at the same time.
This is called combination chemotherapy.
A transplant is when one organ, or part of an organ, is
transferred from a donor to a recipient. For liver cancer patients, a liver
transplant is one treatment option that is considered to be potentially
curative, provided the cancer is indeed confined to the liver.
Few patients with liver cancer are candidates for a liver
transplant. It is not an option for people withsecondary liver cancer, and it
is an option for only a small percentage of people with primary liver cancer. In most cases,
since liver cancer symptoms may not manifest until later stages of the disease,
the cancer may be too large or have spread outside the liver by the time it is
diagnosed.
Complete livertransplant
Liver transplantation is an option for
some patients if the cancer has not spread to other organs, is below a total
maximum size and a suitable liver can be found. The most common transplant
procedure involves complete replacement with a healthy liver from a non-living
donor. This is sometimes called deceased
donor liver transplant (DDLT).
The average wait time for a donor liver
is 796 days.1 Due to
tumor growth (progression) while waiting for a matching liver, most eligible
people will need other medical interventions, such aslocal ablation, before
receiving a liver. These other interventions may help control tumor growth so
the patient can remain on the transplant list. If the cancer spreads outside
the liver or grows too large while a person awaits a liver, he or she may
become ineligible.
Radiation Therapy
Radiation
therapy, sometimes called radiotherapy, is the delivery of high doses of
radiation to a defined local area of the body.
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