Liver cancer or Hepatocellular carcinoma (HCC) is one of the commonest cancers in the world which have a high incidence of Hepatitis B infection. Apart from Hepatitis B, it may be caused by other diseases that lead to cirrhosis of the liver such as Hepatitis C infection, and alcohol abuse.
Unfortunately, like many other cancers, liver cancer may go undetected until a late stage. It is often brought to attention by an ultrasound or CT scan done for pain in the upper abdomen or another unrelated symptom. Liver cancers are malignant tumors that grow on the surface or inside the liver.
Typers of liver cancer are
HepatocellularCarcinoma , Cholangiocarcinoma , Hepatoblastoma and Angiosarcoma or Hemangiosarcoma
Liver cancer is usually diagnosed with a number of different
tests, which may include:
§ Blood
tests: To check your general health and check for a chemical usually found
inincreased levels in people with primary liver cancer.
§ Ultrasound:
A picture of the liver is taken using sound waves.
§ Computed
Tomography (CT) Scan: A specialised x-ray taken from many different angles to
build a three-dimensional (3-D) picture of the body.
§ Magnetic
Resonance Imaging (MRI): Similar to a CT scan, but uses a powerful magnet and
magnetic field instead of x-rays to build an image of the body.
§ Liver
Biopsy: A small piece of liver tissue is removed with a needle and examined for
cancer cells.
§ Laparoscopy:
A small cut in the lower abdomen is made and this allows a thinmini-telescope
(laparoscope) to be inserted to look at the liver and take a sample of liver
tissue.
§ Needle
Biopsy: Needle biopsy, also called image-guided biopsy, is usually performed
using a (MR) to guide the procedure. In many cases, needle biopsies are
performed with the aid of equipment that creates a computer-generated image and
allows radiologists to see an area inside the body from various angles. This
“stereotactic” equipment helps them pinpoint the exact location of the abnormal
tissue.
§ Large
Core Needle Biopsy: In this technique, a special needle is used that enables
the radiologist to obtain a larger biopsy sample. This technique is often used
to obtain tissue samples from lumps or other abnormalities in the breast that
are detected by physical examination or on mammograms or other imaging scans.
moving X-ray technique (fluoroscopy) computed tomography (CT), ultrasound or
magnetic resonance.
Liver Cancer Treatment in
India
§
Surgery: Procedure to remove a portion of the liver. Your doctor
may recommend partial hepatectomy to remove the liver cancer and a small
portion of healthy tissue that surrounds it if your tumor is small and your
liver function is good.
§
Transplant Surgery: During liver transplant surgery, your
diseased liver is removed and replaced with a healthy liver from a donor. Liver
transplant surgery may be an option for people with early-stage liver cancer
who also have cirrhosis.
§
Freezing Cancer Cells: Cryoablation uses extreme cold to destroy
cancer cells. During the procedure, your doctor places the instrument
(cryoprobe) containing liquid nitrogen directly onto liver tumor.
§
Heating Cancer Cells: In a procedure called radiofrequency
ablation, electric current is used to heat and destroy cancer cells. It is also
called hyperthermia cancer treatment.
§
Injecting Alcohol: During alcohol injection, pure alcohol is
injected directly into tumors, either through the skin or during an operation.
Alcohol dries out the cells of the tumor and eventually the cells die.
§
Chemoembolization: A type of chemotherapy treatment that
supplies strong anti-cancer drugs directly to the liver. It is palliative and
not curative treatment.
§
Radiation Therapy: This treatment uses high-powered energy beams
to destroy cancer cells and shrink tumors.
§
Targeted Drug Therapy: Drugs designed to interfere with a
tumor’s ability to generate new blood vessels.
Nonsurgical Treatments for Liver Cancer at World Class
Hospitals in India
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1) Chemoembolization: Chemoembolization is a minimally
invasive treatment for liver cancer that can be used when there is too much
tumor to treat with radiofrequency ablation (RFA), when the tumor is in a
location that cannot be treated with RFA, or in combination with RFA or other
treatments. In this the anticancer drug is given along with another substance
that blocks the hepatic artery. (artery supplying the liver). Thus the
anticancer drug is gets concentrated in the cancerous portion of the liver.2)
Radiofrequency Ablation: For inoperable liver tumors, radiofrequency ablation
(RFA) offers a nonsurgical, localized treatment that kills the tumor cells
with heat, while sparing the healthy liver tissue. Thus, this treatment is
much easier on the patient than systemic therapy.
3) Cryosurgery: It is a treatment that uses an instrument to
freeze and destroy abnormal tissue, such as cancerous cells. This type of
treatment is also called Cryotherapy. The doctor may use ultrasound to guide
the instrument.
4) Drugs called radio-sensitizers may be given with the
radiation therapy to make the cancer cells more sensitive to radiation
therapy.
5) Percutaneous Ethanol Injection: Percutaneous ethanol
injection is a cancer treatment in which a small needle is used to inject
ethanol (alcohol) directly into a tumor to kill cancer cells. The procedure
may be done once or twice a week. Usually local anesthesia is used, but if
the patient has many tumors in the liver, general anesthesia may be needed.
6) Hyperthermia Therapy: Hyperthermia therapy is a type of treatment
in which body tissue is exposed to high temperatures to damage and kill
cancer cells or to make cancer cells more sensitive to the effects of
radiation and certain anticancer drugs. Because some cancer cells are more
sensitive to heat than normal cells are, the cancer cells die and the tumor
shrinks.
7) Biologic Therapy: Biologic therapy is a treatment that uses
the patient’s immune system to fight cancer. Substances made by the body or
made in a laboratory are used to boost, direct, or restore the body’s natural
defenses against cancer. This type of cancer treatment is also called
biotherapy or immunotherapy.
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