Sunday, 4 May 2014

Latest and Advanced Treatment options for Brain Tumor in India


A brain tumor is an abnormal growth of cells within the brain or the central spinal canal. Brain tumors can crop up from the brain cells, the membranes around the brain (known as meninges), nerves, or glands. These damage produce inflammation and places pressure within the skull and compresses the brain tissues. All such tumours are intrinsically serious and life-threatening because of its insidious and infiltrative character in the intracranial cavity.

The following types of brain tumours are seen commonly:

In children: Juvenile pilocytic astrocytoma, craniopharyngioma, medulloblastoma, brainstem glioma and germ cell tumours.

In adults: Astrocytoma, oligodendroglioma, ependymoma, meningioma, vestibular schwannoma and lymphoma. Cancers from other parts of the body can also spread to brain.

What are the common symptoms of brain tumours
 
  • Headaches, usually in the morning
  • Vomiting
  • Convulsions or seizures
  • Weakness in limbs
  • Loss of balance while walking
  • Altered speech or vision
  • Altered behaviour
  • Loss of orientation
  • Memory lapses


Imaging: CT scan or MRI scan of brain is commonly performed.

Biopsy: A piece of tumour is removed for examination by open surgery or in stereotactic fashion using rigid frame to fix skull and localizing tumour under guidance of CT scan or MRI.

How are brain tumours treated?

Brain tumours are treated by surgery, radiation therapy or chemotherapy, or a combination of these. The choice of treatment depends upon the age of the patient, type of tumour, its location, size and grade.

Surgery: Maximum safe resection of the tumour or at least a biopsy is the standard goal of surgery.

Radiation therapy: Radiation kills tumour cells with high energy X-rays, gamma rays or protons. It is usually started after surgery and given over 5-6 weeks.

Chemotherapy: Chemotherapy is the use of drugs to kill cancer cells. It is given orally or through veins. It is given concomitantly with radiation therapy in high-grade tumours. It is also given in recurrent brain tumours after failure of initial treatment.

The Advances Radiation Therapy for Brain Tumours

3-Dimensional Conformal Radiation Therapy (3D-CRT) and Intensity Modulated Radiation Therapy (IMRT):

CT scan and MRI are used to delineate the tumour and computers are used for radiation planning. Only the tumour and the high-risk region surrounding the tumour is radiated, avoiding radiation to
the normal structures in the brain.

Stereotactic Radio-surgery (SRS) and Stereotactic Radiotherapy (SRT): Highly precise immobilization and image guidance system is used for treatment of selected brain tumours. High dose of radiation is delivered only to the tumour with very minimal spillage of dose to the rest of the sensitive brain structures. Stereotactic radiotherapy is preferred in children. Stereotactic radio-surgery delivering high-dose of radiation in single or a very few sessions is performed in adults with tumours such as metastatic residual glioma, meningioma and schwannoma. Novalis-Tx and Cyberknife are advanced machines to deliver such high-precision therapy.

High-definition Rapid Arc: This is the latest software advancement in radiation planning technology. Radiation is delivered in continuous fashion moving the machine head and its small components simultaneously around the patient's head targeting the tumour by infinite small radiation beams. Radiation treatment with such a technique is highly precise and fast. This is preferred in children and elderly patients who cannot lie on treatment couches for long periods.


Proton beam therapy: Proton therapy avoids spillage of radiation dose to the surrounding brain. It is preferred in children as well as in patients with recurrent tumours who have received radiation therapy earlier.


Brain Tumor is no more a scary health condition as modern technology and advanced surgical modalities now offer near perfect clinical outcomes and the patients can soon return to normal life after surgery. 
  • Brain Suite - Intra-operative MR Navigation Microsurgery
  • Trans-Nasal Endoscopic Removal of brain Tumor through the nose
  • Stereotactic Radiosurgery - Gamma Knife & Novalis TX
  • Tumor Embolization using Neuro Interventional Radiology
  • CyberKnife Radiosurgery
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